Compound Activity Prediction with Dose-Dependent Transcriptomic Profiles & Transformer Models
Time: 2:30 pm
day: Day One
Details:
- Leveraging gene-expression profiles to predict activity in biochemical and cellular assays
- Using Transformer models with sequence of transcriptomes from compound treatment over multiple concentrations as input
- Activity predictions validate experimentally, even when transcriptomes are measured in human but activity predicted and tested in Plasmodium parasites
