Compound Activity Prediction with Dose-Dependent Transcriptomic Profiles & Transformer Models

Time: 2:30 pm
day: Day One


  • Leveraging gene-expression profiles to predict activity in biochemical and cellular assays
  • Using Transformer models with sequence of transcriptomes from compound treatment over multiple concentrations as input
  • Activity predictions validate experimentally, even when transcriptomes are measured in human but activity predicted and tested in Plasmodium parasites